Fibroblast growth factor 5 (FGF5) gene, a member of fibroblast growth factor superfamily, plays significant roles in the regulation of the hair growth cycle during the development of mammalian hair follicles as well as the skeletal muscle development.In this study, DNA sequencing was used to scan the putative SNPs within the full-length of FGF5 gen
Poliovirus excretion among children with primary immune deficiency in Pakistan: a pilot surveillance study protocol
Introduction Children with primary immunodeficiency disorders (PID) are more susceptible to developing viral infections and are at a substantially increased risk of developing paralytic poliomyelitis.Such children, if given oral polio vaccines tend to excrete poliovirus chronically that may lead to the propagation of highly divergent vaccine-derive
Vitamin D3 induces mesenchymal-to-endothelial transition and promotes a proangiogenic niche through IGF-1 signaling
Summary: Although vitamin D3 (VitD3) prevents angiogenesis in cancer, VitD3 deficiency is associated with greater incidence of cardiovascular events in patients.We examined the influence of VitD3 on the angiogenic potential of mesenchymal stem cells (MSCs).VitD3 treatment increased the expression of proangiogenic molecules in MSCs, which exhibited